Publications

2024

Backpack-carrying macrophage immunotherapy for periodontitis
Nakajima, M.; Kapate, N.; Clegg, J.R.; Ikeda-Imafuku, M.; Park, K.S. … Journal of Controlled Release 2024, 377, 315-323.

An ionic liquid-based adjuvant for modulating cellular and humoral immune responses
Goetz, M.J.; Park, K.S.; Joshi, M.; Gottlieb, A.P.; Dowling, D.J.; Mitragotri, S. Journal of Controlled Release 2024, 376, 632-645.

Choline geranate (CAGE): A multifaceted ionic liquid for drug delivery
Mitragotri, S. Journal of Controlled Release 2024, 376, 593-600.

Hydrogels in the clinic: An update
Clegg, J.R.; Adebowale, K.; Zhao, Z.; Mitragotri, S. Bioengineering & Translational Medicine 2024, 9 (6), e10680.

Materials for cell surface engineering
Adebowale, K.; Liao, R.; Suja, V.C.; Kapate, N.; Lu, A.; Gao, Y.; Mitragotri, S. Advanced Materials 2024, 36 (43), 2210059.

Choline and geranate ionic liquid for subgingival biofilm control
Yan, C.; Nakajima, M.; Ikeda-Imafuku, M.; Yanagawa, M.; Hayatsu, M.; Fukuta, T. … International Journal of Pharmaceutics 2024, 662, 124544.

Localization of Intramuscular mRNA Delivery Using Deep Eutectic‐Lipid Nanocomposites
Curreri, A.M.; Dunne, M.; Bibbey, M.G.; Kapate, N.; Kim, J.; Mitragotri, S. Advanced Healthcare Materials 2024, 13 (20), 2400327.

Designing drug delivery systems for cell therapy
Wang, L.L.W.; Gao, Y.; Feng, Z; Mooney, D.J.; Mitragotri, S. Nature Reviews Bioengineering 2024, 1-16.

Vaccine adjuvants for infectious disease in the clinic
Morgan, G.; Thotathil, N.; Zhao, Z.; Mitragotri, S. Bioengineering & Translational Medicine 2024, 9 (4).

Dendritic Cell Immune Modulation via Polyphenol Membrane Coatings
Janes, M.E.; Park, K.S.; Gottlieb, A.P.; Curreri, A.; Adebowale, K.; Kim, J. … ACS Applied Materials & Interfaces 2024.

Polymer Micropatches as B-Cell Engagers
Prakash, S.; Kumbhojkar, N.; Gottlieb, A.P.; Park, K.S.; Kapate, N.; Mitragotri, S. ACS Applied Materials & Interfaces 2024.

Polymer Backpack‐Loaded Tissue Infiltrating Monocytes for Treating Cancer
Kapate, N.; Dunne, M.; Gottlieb, A.P.; Mukherji, M.; Suja, V.C.; Prakash, S. … Advanced Healthcare Materials 2024, 2304144.

Vaccine adjuvants for infectious disease in the clinic
Goetz, M.; Thotathil, N.; Zhao, Z.; Mitragotri, S. Bioengineering & Translational Medicine 2024, e10663.

Locoregional drug delivery for cancer therapy: Preclinical progress and clinical translation
Shaha, S.; Rodrigues, D.; Mitragotri, S. Journal of Controlled Release 2024, 367, 737-767.

Neutrophils bearing adhesive polymer micropatches as a drug-free cancer immunotherapy
Kumbhojkar, N.; Prakash, S.; Fukuta, T.; Adu-Berchie, K.; Kapate, N.; An, R. … Nature Biomedical Engineering 2024, 1-14.

Preclinical characterization of macrophage-adhering gadolinium micropatches for MRI contrast after traumatic brain injury in pigs
Wang, L.L.W.; Gao, Y.; Chandran Suja, V.; Boucher, M.L.; Shaha, S.; Kapate, N. … Science Translational Medicine 2024, 16 (728), eadk5413.

Activated neutrophils: A next generation cellular immunotherapy
Kumbhojkar, N.; Mitragotri, S. Bioengineering & Translational Medicine 2024, e10704.

Antibody drug conjugates in the clinic
Udofa, E.; Sankholkar, D.; Mitragotri, S; Zhao, Z. Bioengineering & Translational Medicine 2024, e10677

Hemostats in the clinic
Joshi, M.; Zhao, Z.; Mitragotri, S. Bioengineering & Translational Medicine 2024, e10673.

Backpack-mediated anti-inflammatory macrophage cell therapy for the treatment of traumatic brain injury
Kapate, N.; Liao, R.; Sodemann, R.L.; Stinson, T.; Prakash, S; Kumbhojkar, N. … PNAS Nexus 2024, 3 (1), pgad434.

Cancer vaccines in the clinic
Janes, M.E.; Gottlieb, A.P.; Park, K.S.; Zhao, Z.; Mitragotri, S. Bioengineering & Translational Medicine 2024, 9 (1), e10588.

PEGylated therapeutics in the clinic
Gao, Y.; Joshi, M.; Zhao, Z.; Mitragotri, S. Bioengineering & Translational Medicine 2024, 9 (1), e10600.

2023

Transferrin Receptor‐Targeted Nonspherical Microbubbles for Blood–Brain Barrier Sonopermeation
Dasgupta, A.; Sun, T.; Rama, E.; Motta, A.; Zhang, Y.; Power, C.; Moeckel, D. … Advanced Materials 2023, 35 (52), 2308150.

Dynamics of macrophage tumor infiltration
Adebowale, K.; Guerriero, J.L; Mitragotri, S. Applied Physics Reviews 2023, 10 (4).

A biomimetic chip to assess subcutaneous bioavailability of monoclonal antibodies in humans
Chandran Suja, V.; Qi, Q.M.; Halloran, K.; Zhang, J.; Shaha, S.; Prakash, S. … PNAS Nexus 2023, 2 (10), pgad317.

Liposomal Therapy
Albadawi, H., Mitragotri, S., & Oklu, R. (2023). Introduction to Cancer Biology 3, 436. 

Digital therapeutics in the clinic
Phan, P., Mitragotri, S., & Zhao, Z. (2023). Bioengineering & Translational Medicine, e10536.

A backpack-based myeloid cell therapy for multiple sclerosis
Kapate, N., Dunne, M., Kumbhojkar, N., Prakash, S., Wang, L.L.W., Graveline, A., … (2023). Proceedings of the National Academy of Sciences 120 (17), e2221535120.

A polymer‐based systemic hemostat for managing uncontrolled bleeding
Gao, Y., Ikeda‐Imafuku, M., Zhao, Z., Joshi, M., & Mitragotri, S. (2023). Bioengineering & Translational Medicine, e10516.

Spotlight on Genetic Kidney Diseases: A Call for Drug Delivery and Nanomedicine Solutions
Trac, N., Ashraf, A., Giblin, J., Prakash, S., Mitragotri, S., & Chung, E.J. (2023). ACS Nano 17 (7), 6165-6177.

Nonspherical ultrasound microbubbles
Dasgupta, A., Sun, T., Palomba, R., Rama, E., Zhang, Y., Power, C., Moeckel, D., … (2023). Proceedings of the National Academy of Sciences 120 (13), e2218847120.

Alzheimer's and Parkinson's disease therapies in the clinic
Chopade, P., Chopade, N., Zhao, Z. M., Mitragotri, S., Liao, R., & Suja, V. C. (2023). Bioengineering & Translational Medicine, 8(1).

RNA therapeutics in the clinic
Curreri, A., Sankholkar, D., Mitragotri, S., & Zhao, Z. (2023). Bioengineering & Translational Medicine, 8(1).

Deep Eutectic Solvents for Subcutaneous Delivery of Protein Therapeutics
Curreri, A.M., Kim, J., Dunne, M., Angsantikul, P., Goetz, M., Gao, Y., & Mitragotri, S. (2023). Advanced Science 10 (7), 2205389.

Engineering of bioactive nanocomplexes on dental floss for targeted gingival therapy
Nakajima, M., Nakajima, N., Guo, J., & Mitragotri, S. (2023). Bioengineering & Translational Medicine 8 (2), e10452.

Ultrasound‐mediated delivery of flexibility‐tunable polymer drug conjugates for treating glioblastoma
Sun, T., Krishnan, V., Pan, D.C., Filippov, S.K., Ravid, S., Sarode, A., Kim, J., … (2023). Bioengineering & Translational Medicine 8 (2), e10408. 

Materials for Cell Surface Engineering
Adebowale, K., Liao, R., Suja, V.C., Kapate, N., Lu, A., Gao, Y., & Mitragotri, S. (2023). Advanced Materials, 2210059.

Leadership transition
Mitragotri, S. (2023). Bioengineering & Translational Medicine, 8(1).

2022

Extracellular matrix degrading enzyme with stroma-targeting peptides enhance the penetration of liposomes into tumors
Ikeda-Imafuku, M., Gao, Y. S., Shaha, S., Wang, L. L. W., Park, K. S., Nakajima, M., Adebowale, O., & Mitragotri, S. (2022). Journal of Controlled Release, 352, 1093-1103.

Modularity of RBC hitchhiking with polymeric nanoparticles: testing the limits of non-covalent adsorption
Lenders, V., Escudero, R., Koutsoumpou, X., Alvarez, L. A., Rozenski, J., Soenen, S. J., Zhao, Z. M., Mitragotri, S., Baatsen, P., Allegaert, K., Toelen, J., & Manshian, B. B. (2022). Journal of Nanobiotechnology, 20(1).

Engineering of bioactive nanocomplexes on dental floss for targeted gingival therapy
Nakajima, M., Nakajima, N., Guo, J. L., & Mitragotri, S. (2022). Bioengineering & Translational Medicine.

A Long-Lasting Skin Protectant Based on CG-101, a Deep Eutectic Solvent Comprising Choline and Geranic Acid
Shevachman, M., Mandal, A., Gelston, K., Mitragotri, S., & Joshi, N. (2022). Global Challenges, 6(11).

Ultrasound-mediated delivery of flexibility-tunable polymer drug conjugates for treating glioblastoma
Sun, T., Krishnan, V., Pan, D. C., Filippov, S. K., Ravid, S., Sarode, A., Kim, J., Zhang, Y. Z., Power, C., Aday, S., Guo, J. L., Karp, J. M., McDannold, N. J., & Mitragotri, S. S. (2022). Bioengineering & Translational Medicine.

Red Blood Cell Anchoring Enables Targeted Transduction and Re-Administration of AAV-Mediated Gene Therapy
Zhao, Z. M., Kim, J., Suja, V. C., Kapate, N., Gao, Y. S., Guo, J. L., Muzykantov, V. R., & Mitragotri, S. (2022). Advanced Science, 9(24).

Ionic Liquid-Mediated Transdermal Delivery of Thrombosis-Detecting Nanosensors
Bekdemir, A., Tanner, E. E. L., Kirkpatrick, J., Soleimany, A. P., Mitragotri, S., & Bhatia, S. N. (2022). Adv Healthc Mater, e2102685.

Particle Shape Engineering for Improving Safety and Efficacy of Doxorubicin - a Case Study of Rod-Shaped Carriers in Resistant Small Cell Lung Cancer
Shukla, S. K., A. Sarode, X. Wang, S. Mitragotri, and V. Gupta. Biomater Adv 137 (Jun 2022): 212850.

Viral vector-based gene therapies in the clinic
Zhao, Z.; Anselmo, A. C.; Mitragotri, S. Bioeng Transl Med 2022, 7 (1), e10258.

Imiquimod-gemcitabine nanoparticles harness immune cells to suppress breast cancer
Singh, B.; Maharjan, S.; Pan, D. C.; Zhao, Z.; Gao, Y.; Zhang, Y. S.; Mitragotri, S. Biomaterials 2022, 280, 121302.

Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation Myerson, J. W.; Patel, P. N.; Rubey, K. M.; Zamora, M. E.; Zaleski, M. H.; Habibi, N.; Walsh, L. R.; Lee, Y. W.; Luther, D. C.; Ferguson, L. T.; et al. Nat Nanotechnol 2022, 17 (1), 86-97.

Hyaluronic Acid Nanoparticles for Immunogenic Chemotherapy of Leukemia and T-Cell Lymphoma
Krishnan, V.; Dharamdasani, V.; Bakre, S.; Dhole, V.; Wu, D.; Budnik, B.; Mitragotri, S. Pharmaceutics 2022, 14 (2).

A deep eutectic-based, self-emulsifying subcutaneous depot system for apomorphine therapy in Parkinson's disease
Kim, J.; Gao, Y.; Zhao, Z.; Rodrigues, D.; Tanner, E. E. L.; Ibsen, K.; Sasmal, P. K.; Jaladi, R.; Alikunju, S.; Mitragotri, S. Proc Natl Acad Sci U S A 2022, 119 (9).

Differential Macrophage Responses to Gold Nanostars and Their Implication for Cancer Immunotherapy
Kenry; Eschle, B. K.; Andreiuk, B.; Gokhale, P. C.; Mitragotri, S. Adv Ther-Germany 2022, 5 (3).

Strategies to improve the EPR effect: A mechanistic perspective and clinical translation
M Ikeda-Imafuku, LLW Wang, D Rodrigues, S Shaha et al. Journal of Controlled Release, 2022.

Nanoparticle Properties Influence Transendothelial Migration of Monocytes
Habibi, N.; Brown, T. D.; Adu-Berchie, K.; Christau, S.; Raymond, J. E.; Mooney, D. J.; Mitragotri, S.; Lahann, J. Langmuir 2022.

Injectable hyaluronic acid hydrogels encapsulating drug nanocrystals for long-term treatment of inflammatory arthritis
Gao, Y.; Vogus, D.; Zhao, Z.; He, W.; Krishnan, V.; Kim, J.; Shi, Y.; Sarode, A.; Ukidve, A.; Mitragotri, S. Bioeng Transl Med 2022, 7 (1), e10245.

Dual Affinity to RBCs and Target Cells (DART) Enhances Both Organ-and Cell Type-Targeting of Intravascular Nanocarriers
Ferguson, L. T., Hood, E. D., Shuvaeva, T., Shuvaev, V. V., Basil, M. C., Wang, Z. C., Nong, J., Ma, X. N., Wu, J. C., Myerson, J. W., Marcos-Contreras, O. A., Katzen, J., Carl, J. M., Morrisey, E. E., Cantu, E., Villa, C. H., Mitragotri, S., Muzykantov, V. R., & Brenner, J. S. (2022). ACS Nano, 16(3), 4666-4683.

Ionic Liquid‐Mediated Transdermal Delivery of Thrombosis‐Detecting Nanosensors
A Bekdemir, EEL Tanner, J Kirkpatrick, AP Soleimany… - Advanced Healthcare Materials, 2022.

2021

Systemic tumour suppression via the preferential accumulation of erythrocyte-anchored chemokine-encapsulating nanoparticles in lung metastases
Zhao, Z.; Ukidve, A.; Krishnan, V.; Fehnel, A.; Pan, D. C.; Gao, Y.; Kim, J.; Evans, M. A.; Mandal, A.; Guo, J.; et al. Nat Biomed Eng 2021, 5 (5), 441-454.

Ionic Liquid-Enabled Topical Delivery of Immunomodulators
Zhao, Z.; Tanner, E. E. L.; Kim, J.; Ibsen, K.; Gao, Y.; Mitragotri, S. ACS Biomater Sci Eng 2021, 7 (6), 2783-2790.

Gemcitabine and doxorubicin in immunostimulatory monophosphoryl lipid A liposomes for treating breast cancer
Wu, D.; Zhao, Z.; Kim, J.; Razmi, A.; Wang, L. L.; Kapate, N.; Gao, Y.; Peng, K.; Ukidve, A.; Mitragotri, S. Bioeng Transl Med 2021, 6 (1), e10188.

Optimized 5-Fluorouridine Prodrug for Co-Loading with Doxorubicin in Clinically Relevant Liposomes
Wu, D.; Vogus, D.; Krishnan, V.; Broto, M.; Pusuluri, A.; Zhao, Z.; Kapate, N.; Mitragotri, S. Pharmaceutics 2021, 13 (1).

Cell therapies in the clinic
Wang, L. L.; Janes, M. E.; Kumbhojkar, N.; Kapate, N.; Clegg, J. R.; Prakash, S.; Heavey, M. K.; Zhao, Z.; Anselmo, A. C.; Mitragotri, S. Bioeng Transl Med 2021, 6 (2), e10214.

The evolution of commercial drug delivery technologies
Vargason, A. M.; Anselmo, A. C.; Mitragotri, S. Nat Biomed Eng 2021, 5 (9), 951-967.

Overcoming biological barriers to improve solid tumor immunotherapy
Ukidve, A.; Cu, K.; Kumbhojkar, N.; Lahann, J.; Mitragotri, S. Drug Deliv Transl Res 2021, 11 (6), 2276-2301.

Bioinspired particle engineering for non-invasive inhaled drug delivery to the lungs
Shukla, S. K.; Sarode, A.; Kanabar, D. D.; Muth, A.; Kunda, N. K.; Mitragotri, S.; Gupta, V. Mater Sci Eng C Mater Biol Appl 2021, 128, 112324.

Enhancement of Anticancer Efficacy and Tumor Penetration of Sorafenib by Ionic Liquids
Shi, Y.; Zhao, Z.; Peng, K.; Gao, Y.; Wu, D.; Kim, J.; Mitragotri, S. Adv Healthc Mater 2021, 10 (2), e2001455.

A dual macrophage polarizer conjugate for synergistic melanoma therapy
Sallam, M. A.; Wyatt Shields Iv, C.; Prakash, S.; Kim, J.; Pan, D. C.; Mitragotri, S. J Control Release 2021, 335, 333-344.

Formulation-based approaches for dermal delivery of vaccines and therapeutic nucleic acids: Recent advances and future perspectives
Sallam, M. A.; Prakash, S.; Kumbhojkar, N.; Shields, C. W. t.; Mitragotri, S. Bioeng Transl Med 2021, 6 (3), e10215.

Modulation of Gastrointestinal Mucus Properties with Ionic Liquids for Drug Delivery
Peng, K.; Gao, Y.; Angsantikul, P.; LaBarbiera, A.; Goetz, M.; Curreri, A. M.; Rodrigues, D.; Tanner, E. E. L.; Mitragotri, S. Adv Healthc Mater 2021, 10 (13), e2002192.

Hyaluronic acid-doxorubicin nanoparticles for targeted treatment of colorectal cancer
Pan, D. C.; Krishnan, V.; Salinas, A. K.; Kim, J.; Sun, T.; Ravid, S.; Peng, K.; Wu, D.; Nurunnabi, M.; Nelson, J. A.; et al. Bioeng Transl Med 2021, 6 (1), e10166.

Topical treatment of periodontitis using an iongel
Nakajima, M.; Tanner, E. E. L.; Nakajima, N.; Ibsen, K. N.; Mitragotri, S. Biomaterials 2021, 276, 121069.

Noninvasive Assessment of Epidermal Genomic Markers of UV Exposure in Skin
Muradova, E.; Patel, N.; Sell, B.; Bittencourt, B. B.; Ojeda, S. S.; Adelmann, C. H.; Cen, L.; Cheng, C. H.; Shen, J.; Davis, C. M.; et al. J Invest Dermatol 2021, 141 (1), 124-131 e122.

Enhancement of elastin expression by transdermal administration of sialidase isozyme Neu2
Minami, A.; Fujita, Y.; Goto, J.; Iuchi, A.; Fujita, K.; Mikami, Y.; Shiratori, M.; Ishii, A.; Mitragotri, S.; Iwao, Y.; et al. Sci Rep 2021, 11 (1), 3302.

Hyaluronic acid conjugates for topical treatment of skin cancer lesions
Krishnan, V.; Peng, K.; Sarode, A.; Prakash, S.; Zhao, Z.; Filippov, S. K.; Todorova, K.; Sell, B. R.; Lujano, O.; Bakre, S.; et al. Sci Adv 2021, 7 (24).

Clinical translation of choline and geranic acid deep eutectic solvent
Ko, J.; Mandal, A.; Dhawan, S.; Shevachman, M.; Mitragotri, S.; Joshi, N. Bioeng Transl Med 2021, 6 (2), e10191.

A Deep Eutectic Solvent-Based Approach to Intravenous Formulation
Kim, J.; Shi, Y.; Kwon, C. J.; Gao, Y.; Mitragotri, S. Adv Healthc Mater 2021, 10 (18), e2100585.

Non-spherical micro- and nanoparticles for drug delivery: Progress over 15 years
Kapate, N.; Clegg, J. R.; Mitragotri, S. Adv Drug Deliv Rev 2021, 177, 113807.

Red blood cells: The metamorphosis of a neglected carrier into the natural mothership for artificial nanocarriers
Glassman, P. M.; Hood, E. D.; Ferguson, L. T.; Zhao, Z.; Siegel, D. L.; Mitragotri, S.; Brenner, J. S.; Muzykantov, V. R. Adv Drug Deliv Rev 2021, 178, 113992.

Covalently Crosslinked Hydrogels via Step-Growth Reactions: Crosslinking Chemistries, Polymers, and Clinical Impact
Gao, Y.; Peng, K.; Mitragotri, S. Adv Mater 2021, 33 (25), e2006362.

Recent Advances in Ionic Liquids in Biomedicine
Curreri, A. M.; Mitragotri, S.; Tanner, E. E. L. Adv Sci (Weinh) 2021, 8 (17), e2004819.

Red Blood Cell Hitchhiking: A Novel Approach for Vascular Delivery of Nanocarriers
Brenner, J. S.; Mitragotri, S.; Muzykantov, V. R. Annu Rev Biomed Eng 2021, 23, 225-248.

Nanoparticles in the clinic: An update post COVID-19 vaccines
Anselmo, A. C.; Mitragotri, S. Bioeng Transl Med 2021, e10246.

Ionic Liquids and Deep Eutectic Solvents for Enhanced Delivery of Antibodies in the Gastrointestinal Tract
Angsantikul, P., Peng, K. V., Curreri, A. M., Chua, Y., Chen, K. V. Z., Ehondor, J., & Mitragotri, S. (2021). Advanced Functional Materials, 31(44).

Percutaneous liquid ablation agent for tumor treatment and drug delivery
Albadawi, H.; Zhang, Z.; Altun, I.; Hu, J.; Jamal, L.; Ibsen, K. N.; Tanner, E. E. L.; Mitragotri, S.; Oklu, R. Sci Transl Med 2021, 13 (580).

Targeting Strategies for Tissue-Specific Drug Delivery
Zhao, Z.; Ukidve, A.; Kim, J.; Mitragotri, S. Cell 2020, 181 (1), 151-167.

Engineering of Living Cells with Polyphenol-Functionalized Biologically Active Nanocomplexes
Zhao, Z.; Pan, D. C.; Qi, Q. M.; Kim, J.; Kapate, N.; Sun, T.; Shields, C. W. t.; Wang, L. L.; Wu, D.; Kwon, C. J.; et al. Adv Mater 2020, 32 (49), e2003492.

Topical Application of Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells in Combination with Sponge Spicules for Treatment of Photoaging
Zhang, K.; Yu, L.; Li, F. R.; Li, X.; Wang, Z.; Zou, X.; Zhang, C.; Lv, K.; Zhou, B.; Mitragotri, S.; et al. Int J Nanomedicine 2020, 15, 2859-2872.

Design principles of drug combinations for chemotherapy
Wu, D.; Pusuluri, A.; Vogus, D.; Krishnan, V.; Shields, C. W. t.; Kim, J.; Razmi, A.; Mitragotri, S. J Control Release 2020, 323, 36-46.

Development of inhalable quinacrine loaded bovine serum albumin modified cationic nanoparticles: Repurposing quinacrine for lung cancer therapeutics
Vaidya, B.; Kulkarni, N. S.; Shukla, S. K.; Parvathaneni, V.; Chauhan, G.; Damon, J. K.; Sarode, A.; Garcia, J. V.; Kunda, N.; Mitragotri, S.; et al. Int J Pharm 2020, 577, 118995.

Ionic liquid-mediated delivery of insulin to buccal mucosa
Vaidya, A.; Mitragotri, S. J Control Release 2020, 327, 26-34.

Erythrocyte-driven immunization via biomimicry of their natural antigen-presenting function
Ukidve, A.; Zhao, Z.; Fehnel, A.; Krishnan, V.; Pan, D. C.; Gao, Y.; Mandal, A.; Muzykantov, V.; Mitragotri, S. Proc Natl Acad Sci U S A 2020, 117 (30), 17727-17736.

Ionic-Liquid-Based Safe Adjuvants
Ukidve, A.; Cu, K.; Goetz, M.; Angsantikul, P.; Curreri, A.; Tanner, E. E. L.; Lahann, J.; Mitragotri, S. Adv Mater 2020, 32 (46), e2002990.

Stabilization and Topical Skin Delivery of Framework Nucleic Acids using Ionic Liquids
Tanner, E. E. L.; Wiraja, C.; Curreri, C. A.; Xu, C. J.; Mitragotri, S. Adv Ther-Germany 2020, 3 (7).

Physical triggering strategies for drug delivery
Sun, T.; Dasgupta, A.; Zhao, Z.; Nurunnabi, M.; Mitragotri, S. Adv Drug Deliv Rev 2020, 158, 36-62.

Harnessing cells to deliver nanoparticle drugs to treat cancer
Singh, B.; Mitragotri, S. Biotechnol Adv 2020, 42, 107339.

Materials for Immunotherapy
Shields, C. W. t.; Wang, L. L.; Evans, M. A.; Mitragotri, S. Adv Mater 2020, 32 (13), e1901633.

Cellular backpacks for macrophage immunotherapy
Shields, C. W. t.; Evans, M. A.; Wang, L. L.; Baugh, N.; Iyer, S.; Wu, D.; Zhao, Z.; Pusuluri, A.; Ukidve, A.; Pan, D. C.; et al. Sci Adv 2020, 6 (18), eaaz6579.

Oral delivery of sorafenib through spontaneous formation of ionic liquid nanocomplexes
Shi, Y.; Zhao, Z.; Gao, Y.; Pan, D. C.; Salinas, A. K.; Tanner, E. E. L.; Guo, J.; Mitragotri, S. J Control Release 2020, 322, 602-609.

Layered self-assemblies for controlled drug delivery: A translational overview
Sarode, A.; Annapragada, A.; Guo, J.; Mitragotri, S. Biomaterials 2020, 242, 119929.

Hyaluronic Acid Conjugates of Vorinostat and Bexarotene for Treatment of Cutaneous Malignancies
Sallam, M. A., Prakash, S., Krishnan, V., Todorova, K., Mandinova, A., & Mitragotri, S. (2020). Advanced Therapeutics, 3(10).

Multifunctional Synthetic Protein Nanoparticles via Reactive Electrojetting
Quevedo, D. F.; Habibi, N.; Gregory, J. V.; Hernandez, Y.; Brown, T. D.; Miki, R.; Plummer, B. N.; Rahmani, S.; Raymond, J. E.; Mitragotri, S.; et al. Macromol Rapid Commun 2020, 41 (23), e2000425.

Reply to Peiretti et al.: Effect of CAGE on fat uptake and food intake
Nurunnabi, M.; Ibsen, K. N.; Tanner, E. E. L.; Mitragotri, S. Proc Natl Acad Sci U S A 2020, 117 (15), 8249.

Size, shape, and flexibility influence nanoparticle transport across brain endothelium under flow
Nowak, M.; Brown, T. D.; Graham, A.; Helgeson, M. E.; Mitragotri, S. Bioeng Transl Med 2020, 5 (2), e10153.

The Future is Bright
Mitragotri, S.; Anselmo, A. C. BioTM Buzz (Volume 5, Issue 3): Bioeng Transl Med 2020, 5 (3), e10185.

Year 2020 in review
Mitragotri, S. Bioengineering & Translational Medicine: Bioeng Transl Med 2020, 5 (3), e10178.

Treatment of psoriasis with NFKBIZ siRNA using topical ionic liquid formulations
Mandal, A.; Kumbhojkar, N.; Reilly, C.; Dharamdasani, V.; Ukidve, A.; Ingber, D. E.; Mitragotri, S. Sci Adv 2020, 6 (30), eabb6049.

Hydrogels in the clinic
Mandal, A.; Clegg, J. R.; Anselmo, A. C.; Mitragotri, S. Bioeng Transl Med 2020, 5 (2), e10158.

Coupled influences of particle shape, surface property and flow hydrodynamics on rod-shaped colloid transport in porous media
Ma, H.; Bolster, C.; Johnson, W. P.; Li, K.; Pazmino, E.; Camacho, K. M.; Anselmo, A. C.; Mitragotri, S. e J Colloid InterfacSci 2020, 577, 471-480.

Correlations Between Skin Barrier Integrity and Delivery of Hydrophilic Molecules in the Presence of Penetration Enhancers
Lin, X.; Wang, Z.; Ou, H.; Mitragotri, S.; Chen, M. Pharm Res 2020, 37 (6), 100.

Skin Delivery of siRNA Using Sponge Spicules in Combination with Cationic Flexible Liposomes
Liang, X.; Zhang, J.; Ou, H.; Chen, J.; Mitragotri, S.; Chen, M. Mol Ther Nucleic Acids 2020, 20, 639-648.

Nanoparticles for topical drug delivery: Potential for skin cancer treatment
Krishnan, V.; Mitragotri, S. Adv Drug Deliv Rev 2020, 153, 87-108.

The Search for Antifungal Prophylaxis After Artificial Corneal Surgery-An In Vitro Study
Kim, S.; Bispo, P. J. M.; Tanner, E. E. L.; Mitragotri, S.; RN, E. S.; Gipson, I.; Chodosh, J.; Behlau, I.; Paschalis, E. I.; Gilmore, M. S.; et al. Cornea 2020, 39 (12), 1547-1555.

Drug delivery to macrophages: A review of targeting drugs and drug carriers to macrophages for inflammatory diseases
He, W.; Kapate, N.; Shields, C. W. t.; Mitragotri, S. Adv Drug Deliv Rev 2020, 165-166, 15-40.

Author Correction: Transdermal delivery of nobiletin using ionic liquids
Hattori, T.; Tagawa, H.; Inai, M.; Kan, T.; Kimura, S. I.; Itai, S.; Mitragotri, S.; Iwao, Y. Sci Rep 2020, 10 (1), 3967.

Protein-avoidant ionic liquid (PAIL)-coated nanoparticles to increase bloodstream circulation and drive biodistribution
Hamadani, C. M.; Goetz, M. J.; Mitragotri, S.; Tanner, E. E. L. Sci Adv 2020, 6 (48).

Molecular mechanism of the skin permeation enhancing effect of ethanol: a molecular dynamics study
Gupta, R.; Badhe, Y.; Rai, B.; Mitragotri, S. RSC Adv 2020, 10 (21), 12234-12248.

Permeation of nanoparticles across the intestinal lipid membrane: dependence on shape and surface chemistry studied through molecular simulations
Gupta, R.; Badhe, Y.; Mitragotri, S.; Rai, B. Nanoscale 2020, 12 (11), 6318-6333.

Programmable Delivery of Synergistic Cancer Drug Combinations Using Bicompartmental Nanoparticles
Gregory, J. V.; Vogus, D. R.; Barajas, A.; Cadena, M. A.; Mitragotri, S.; Lahann, J. Adv Healthc Mater 2020, 9 (21), e2000564.

Vascular Drug Delivery Using Carrier Red Blood Cells: Focus on RBC Surface Loading and Pharmacokinetics
Glassman, P. M.; Villa, C. H.; Ukidve, A.; Zhao, Z.; Smith, P.; Mitragotri, S.; Russell, A. J.; Brenner, J. S.; Muzykantov, V. R. Pharmaceutics 2020, 12 (5).

A polymer-based systemic hemostatic agent
Gao, Y.; Sarode, A.; Kokoroskos, N.; Ukidve, A.; Zhao, Z.; Guo, S.; Flaumenhaft, R.; Gupta, A. S.; Saillant, N.; Mitragotri, S. Sci Adv 2020, 6 (31), eaba0588.

Investigating the potential use of an ionic liquid (1-Butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide) as an anti-fungal treatment against the amphibian chytrid fungus, Batrachochytrium dendrobatidis
DiRenzo, G. V.; Chen, R.; Ibsen, K.; Toothman, M.; Miller, A. J.; Gershman, A.; Mitragotri, S.; Briggs, C. J. PLoS One 2020, 15 (4), e0231811.

Topical delivery of siRNA into skin using ionic liquids
Dharamdasani, V.; Mandal, A.; Qi, Q. M.; Suzuki, I.; Bentley, M.; Mitragotri, S. J Control Release 2020, 323, 475-482.

Delivery Strategies for Skin: Comparison of Nanoliter Jets, Needles and Topical Solutions
Cu, K.; Bansal, R.; Mitragotri, S.; Fernandez Rivas, D. Ann Biomed Eng 2020, 48 (7), 2028-2039.

Effect of Nanoparticle Composition, Size, Shape, and Stiffness on Penetration Across the Blood-Brain Barrier
Brown, T. D.; Habibi, N.; Wu, D.; Lahann, J.; Mitragotri, S. ACS Biomater Sci Eng 2020, 6 (9), 4916-4928.

Amphiphilic Polyacrylamide Excipients Lead to a Record-Breaking Fast-Acting Insulin
Angsantikul, P.; Mitragotri, S. Trends Pharmacol Sci 2020, 41 (10), 681-684.

Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers
Zhao, Z.; Ukidve, A.; Krishnan, V.; Mitragotri, S. Adv Drug Deliv Rev 2019, 143, 3-21.

Erythrocyte leveraged chemotherapy (ELeCt): Nanoparticle assembly on erythrocyte surface to combat lung metastasis
Zhao, Z.; Ukidve, A.; Gao, Y.; Kim, J.; Mitragotri, S. Sci Adv 2019, 5 (11), eaax9250.

Skin delivery of hyaluronic acid by the combined use of sponge spicules and flexible liposomes
Zhang, C.; Zhang, K.; Zhang, J.; Ou, H.; Duan, J.; Zhang, S.; Wang, D.; Mitragotri, S.; Chen, M. Biomater Sci 2019, 7 (4), 1299-1310.

Cyclodextrin modified erlotinib loaded PLGA nanoparticles for improved therapeutic efficacy against non-small cell lung cancer
Vaidya, B.; Parvathaneni, V.; Kulkarni, N. S.; Shukla, S. K.; Damon, J. K.; Sarode, A.; Kanabar, D.; Garcia, J. V.; Mitragotri, S.; Muth, A.; et al. Int J Biol Macromol 2019, 122, 338-347.

The Influence of Water on Choline-Based Ionic Liquids
Tanner, E. E. L.; Piston, K. M.; Ma, H.; Ibsen, K. N.; Nangia, S.; Mitragotri, S. ACS Biomater Sci Eng 2019, 5 (7), 3645-3653.

Design Principles of Ionic Liquids for Transdermal Drug Delivery
Tanner, E. E. L.; Curreri, A. M.; Balkaran, J. P. R.; Selig-Wober, N. C.; Yang, A. B.; Kendig, C.; Fluhr, M. P.; Kim, N.; Mitragotri, S. Adv Mater 2019, 31 (27), e1901103.

Mechanistic study of transdermal delivery of macromolecules assisted by ionic liquids
Qi, Q. M.; Mitragotri, S. J Control Release 2019, 311-312, 162-169.

Immunological consequences of chemotherapy: Single drugs, combination therapies and nanoparticle-based treatments
Pusuluri, A.; Wu, D.; Mitragotri, S. J Control Release 2019, 305, 130-154.

Role of synergy and immunostimulation in design of chemotherapy combinations: An analysis of doxorubicin and camptothecin
Pusuluri, A.; Krishnan, V.; Wu, D.; Shields, C. W. t.; Wang, L. W.; Mitragotri, S. Bioeng Transl Med 2019, 4 (2), e10129.

Treating Tumors at Low Drug Doses Using an Aptamer-Peptide Synergistic Drug Conjugate
Pusuluri, A.; Krishnan, V.; Lensch, V.; Sarode, A.; Bunyan, E.; Vogus, D. R.; Menegatti, S.; Soh, H. T.; Mitragotri, S. Angew Chem Int Ed Engl 2019, 58 (5), 1437-1441.

Oral ionic liquid for the treatment of diet-induced obesity
Nurunnabi, M.; Ibsen, K. N.; Tanner, E. E. L.; Mitragotri, S. Proc Natl Acad Sci U S A 2019, 116 (50), 25042-25047.

Editorial: The launch phase of Bioengineering & Translational Medicine
Mitragotri, S. Bioeng Transl Med 2019, 4 (3), e10140.

Shape-based separation of synthetic microparticles
Mage, P. L.; Csordas, A. T.; Brown, T.; Klinger, D.; Eisenstein, M.; Mitragotri, S.; Hawker, C.; Soh, H. T. Nat Mater 2019, 18 (1), 82-89.

On the issue of transparency and reproducibility in nanomedicine
Leong, H. S.; Butler, K. S.; Brinker, C. J.; Azzawi, M.; Conlan, S.; Dufes, C.; Owen, A.; Rannard, S.; Scott, C.; Chen, C.; et al. Nat Nanotechnol 2019, 14 (7), 629-635.

Publisher Correction: On the issue of transparency and reproducibility in nanomedicine
Leong, H. S.; Butler, K. S.; Brinker, C. J.; Azzawi, M.; Conlan, S.; Dufes, C.; Owen, A.; Rannard, S.; Scott, C.; Chen, C.; et al. Nat Nanotechnol 2019, 14 (8), 811.

Nanocrystals: A perspective on translational research and clinical studies
Jarvis, M.; Krishnan, V.; Mitragotri, S. Bioeng Transl Med 2019, 4 (1), 5-16.

Transdermal delivery of nobiletin using ionic liquids
Hattori, T.; Tagawa, H.; Inai, M.; Kan, T.; Kimura, S. I.; Itai, S.; Mitragotri, S.; Iwao, Y. Sci Rep 2019, 9 (1), 20191.

Effect of Chemical Permeation Enhancers on Skin Permeability: In silico screening using Molecular Dynamics simulations
Gupta, R.; Dwadasi, B. S.; Rai, B.; Mitragotri, S. Sci Rep 2019, 9 (1), 1456.

Shape effect in active targeting of nanoparticles to inflamed cerebral endothelium under static and flow conditions
Da Silva-Candal, A.; Brown, T.; Krishnan, V.; Lopez-Loureiro, I.; Avila-Gomez, P.; Pusuluri, A.; Perez-Diaz, A.; Correa-Paz, C.; Hervella, P.; Castillo, J.; et al. J Control Release 2019, 309, 94-105.

A microfluidic model of human brain (muHuB) for assessment of blood brain barrier
Brown, T. D.; Nowak, M.; Bayles, A. V.; Prabhakarpandian, B.; Karande, P.; Lahann, J.; Helgeson, M. E.; Mitragotri, S. Bioeng Transl Med 2019, 4 (2), e10126.

Intestinal iontophoresis from mucoadhesive patches: a strategy for oral delivery
Banerjee, A.; Chen, R.; Arafin, S.; Mitragotri, S. J Control Release 2019, 297, 71-78.

Nanoparticles in the clinic: An update
Anselmo, A. C.; Mitragotri, S. Bioeng Transl Med 2019, 4 (3), e10143.

Non-invasive delivery strategies for biologics
Anselmo, A. C.; Gokarn, Y.; Mitragotri, S. Nat Rev Drug Discov 2019, 18 (1), 19-40.

Transdermal immunomodulation: Principles, advances and perspectives
Zhao, Z.; Ukidve, A.; Dasgupta, A.; Mitragotri, S. Adv Drug Deliv Rev 2018, 127, 3-19.

Controlling Complex Nanoemulsion Morphology Using Asymmetric Cosurfactants for the Preparation of Polymer Nanocapsules
Zhang, M.; Corona, P. T.; Ruocco, N.; Alvarez, D.; Malo de Molina, P.; Mitragotri, S.; Helgeson, M. E. Langmuir 2018, 34 (3), 978-990.

Schedule dependent synergy of gemcitabine and doxorubicin: Improvement of in vitro efficacy and lack of in vitro-in vivo correlation
Vogus, D. R.; Pusuluri, A.; Chen, R.; Mitragotri, S. Bioeng Transl Med 2018, 3 (1), 49-57.

Transdermal insulin delivery using choline-based ionic liquids (CAGE)
Tanner, E. E. L.; Ibsen, K. N.; Mitragotri, S. J Control Release 2018, 286, 137-144.

Nanoparticle Properties Modulate Their Attachment and Effect on Carrier Red Blood Cells
Pan, D. C.; Myerson, J. W.; Brenner, J. S.; Patel, P. N.; Anselmo, A. C.; Mitragotri, S.; Muzykantov, V. Sci Rep 2018, 8 (1), 1615.

Engineering clinical translation-Introduction to Special Issue Dedicated to 2017 Bioengineering and Translational Medicine Conference
Kannan, R. M.; Mitragotri, S. Bioeng Transl Med 2018, 3 (2), 73.

Engineering clinical translation-Introduction to Special Issue Dedicated to 2017 Bioengineering and Translational Medicine Conference
Kannan, R. M.; Mitragotri, S. Bioeng Transl Med 2018, 3 (3), 185.

Detachment of ligands from nanoparticle surface under flow and endothelial cell contact: Assessment using microfluidic devices
Jarvis, M.; Arnold, M.; Ott, J.; Krishnan, V.; Pant, K.; Prabhakarpandian, B.; Mitragotri, S. Bioeng Transl Med 2018, 3 (2), 148-155.

Mechanism of Antibacterial Activity of Choline-Based Ionic Liquids (CAGE)
Ibsen, K. N.; Ma, H.; Banerjee, A.; Tanner, E. E. L.; Nangia, S.; Mitragotri, S. ACS Biomater Sci Eng 2018, 4 (7), 2370-2379.

Macrophage-mediated delivery of light activated nitric oxide prodrugs with spatial, temporal and concentration control
Evans, M. A.; Huang, P. J.; Iwamoto, Y.; Ibsen, K. N.; Chan, E. M.; Hitomi, Y.; Ford, P. C.; Mitragotri, S. Chem Sci 2018, 9 (15), 3729-3741.

Influence of particle size and shape on their margination and wall-adhesion: implications in drug delivery vehicle design across nano-to-micro scale
Cooley, M.; Sarode, A.; Hoore, M.; Fedosov, D. A.; Mitragotri, S.; Sen Gupta, A. Nanoscale 2018, 10 (32), 15350-15364.

Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude
Brenner, J. S.; Pan, D. C.; Myerson, J. W.; Marcos-Contreras, O. A.; Villa, C. H.; Patel, P.; Hekierski, H.; Chatterjee, S.; Tao, J. Q.; Parhiz, H.; et al. Nat Commun 2018, 9 (1), 2684.

Ionic liquids for oral insulin delivery
Banerjee, A.; Ibsen, K.; Brown, T.; Chen, R.; Agatemor, C.; Mitragotri, S. Proc Natl Acad Sci U S A 2018, 115 (28), 7296-7301.

Reply to Rogers and Gurau: Definitions of ionic liquids and deep eutectic solvents
Banerjee, A.; Ibsen, K.; Brown, T.; Chen, R.; Agatemor, C.; Mitragotri, S. Proc Natl Acad Sci U S A 2018, 115 (47), E11000-E11001.

Ionic liquids for addressing unmet needs in healthcare
Agatemor, C.; Ibsen, K. N.; Tanner, E. E. L.; Mitragotri, S. Bioeng Transl Med 2018, 3 (1), 7-25.

Skin Delivery of Hydrophilic Biomacromolecules Using Marine Sponge Spicules
Zhang, S.; Ou, H.; Liu, C.; Zhang, Y.; Mitragotri, S.; Wang, D.; Chen, M. Mol Pharm 2017, 14 (9), 3188-3200.

Synthesis of Oil-Laden Poly(ethylene glycol) Diacrylate Hydrogel Nanocapsules from Double Nanoemulsions
Zhang, M.; Nowak, M.; Malo de Molina, P.; Abramovitch, M.; Santizo, K.; Mitragotri, S.; Helgeson, M. E. Langmuir 2017, 33 (24), 6116-6126.

Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes
Wibroe, P. P.; Anselmo, A. C.; Nilsson, P. H.; Sarode, A.; Gupta, V.; Urbanics, R.; Szebeni, J.; Hunter, A. C.; Mitragotri, S.; Mollnes, T. E.; et al. Nat Nanotechnol 2017, 12 (6), 589-594.

A hyaluronic acid conjugate engineered to synergistically and sequentially deliver gemcitabine and doxorubicin to treat triple negative breast cancer
Vogus, D. R.; Evans, M. A.; Pusuluri, A.; Barajas, A.; Zhang, M.; Krishnan, V.; Nowak, M.; Menegatti, S.; Helgeson, M. E.; Squires, T. M.; et al. J Control Release 2017, 267, 191-202.

Introduction to Special Issue: 2016 Translational Medicine and Bioengineering Conference
Rege, K.; Mitragotri, S. Bioeng Transl Med 2017, 2 (2), 137-138.

Engineering live cell surfaces with functional polymers via cytocompatible controlled radical polymerization
Niu, J.; Lunn, D. J.; Pusuluri, A.; Yoo, J. I.; O'Malley, M. A.; Mitragotri, S.; Soh, H. T.; Hawker, C. J. Nat Chem 2017, 9 (6), 537-545.

Drug Delivery Research for the Future: Expanding the Nano Horizons and Beyond
Mitragotri, S.; Lammers, T.; Bae, Y. H.; Schwendeman, S.; De Smedt, S.; Leroux, J. C.; Peer, D.; Kwon, I. C.; Harashima, H.; Kikuchi, A.; et al. J Control Release 2017, 246, 183-184.

Influence of Particle Geometry on Gastrointestinal Transit and Absorption following Oral Administration
Li, D.; Zhuang, J.; He, H.; Jiang, S.; Banerjee, A.; Lu, Y.; Wu, W.; Mitragotri, S.; Gan, L.; Qi, J. ACS Appl Mater Interfaces 2017, 9 (49), 42492-42502.

Microfluidic co-culture devices to assess penetration of nanoparticles into cancer cell mass
Jarvis, M.; Arnold, M.; Ott, J.; Pant, K.; Prabhakarpandian, B.; Mitragotri, S. Bioeng Transl Med 2017, 2 (3), 268-277.

Intestinal micropatches for oral insulin delivery
Banerjee, A.; Wong, J.; Gogoi, R.; Brown, T.; Mitragotri, S. J Drug Target 2017, 25 (7), 608-615.

Intestinal patch systems for oral drug delivery
Banerjee, A.; Mitragotri, S. Curr Opin Pharmacol 2017, 36, 58-65.

Transdermal Protein Delivery Using Choline and Geranate (CAGE) Deep Eutectic Solvent
Banerjee, A.; Ibsen, K.; Iwao, Y.; Zakrewsky, M.; Mitragotri, S. Adv Healthc Mater 2017, 6 (15).

Impact of particle elasticity on particle-based drug delivery systems
Anselmo, A. C.; Mitragotri, S. Adv Drug Deliv Rev 2017, 108, 51-67.

Therapeutic RNAi robed with ionic liquid moieties as a simple, scalable prodrug platform for treating skin disease
Zakrewsky, M.; Mitragotri, S. J Control Release 2016, 242, 80-88.

Choline and Geranate Deep Eutectic Solvent as a Broad-Spectrum Antiseptic Agent for Preventive and Therapeutic Applications
Zakrewsky, M.; Banerjee, A.; Apte, S.; Kern, T. L.; Jones, M. R.; Sesto, R. E.; Koppisch, A. T.; Fox, D. T.; Mitragotri, S. Adv Healthc Mater 2016, 5 (11), 1282-1289.

Red blood cells: Supercarriers for drugs, biologicals, and nanoparticles and inspiration for advanced delivery systems
Villa, C. H.; Anselmo, A. C.; Mitragotri, S.; Muzykantov, V. Adv Drug Deliv Rev 2016, 106 (Pt A), 88-103.

The Effect of Polymeric Nanoparticles on Biocompatibility of Carrier Red Blood Cells
Pan, D.; Vargas-Morales, O.; Zern, B.; Anselmo, A. C.; Gupta, V.; Zakrewsky, M.; Mitragotri, S.; Muzykantov, V. PLoS One 2016, 11 (3), e0152074.

Non-affinity factors modulating vascular targeting of nano- and microcarriers
Myerson, J. W.; Anselmo, A. C.; Liu, Y.; Mitragotri, S.; Eckmann, D. M.; Muzykantov, V. R. Adv Drug Deliv Rev 2016, 99 (Pt A), 97-112.

De Novo Design of Skin-Penetrating Peptides for Enhanced Transdermal Delivery of Peptide Drugs
Menegatti, S.; Zakrewsky, M.; Kumar, S.; De Oliveira, J. S.; Muraski, J. A.; Mitragotri, S. Adv Healthc Mater 2016, 5 (5), 602-609.

Delivery of Exenatide and Insulin Using Mucoadhesive Intestinal Devices
Gupta, V.; Hwang, B. H.; Doshi, N.; Banerjee, A.; Anselmo, A. C.; Mitragotri, S. Ann Biomed Eng 2016, 44 (6), 1993-2007.

DAFODIL: A novel liposome-encapsulated synergistic combination of doxorubicin and 5FU for low dose chemotherapy
Camacho, K. M.; Menegatti, S.; Vogus, D. R.; Pusuluri, A.; Fuchs, Z.; Jarvis, M.; Zakrewsky, M.; Evans, M. A.; Chen, R.; Mitragotri, S. J Control Release 2016, 229, 154-162.

Low-molecular-weight polymer-drug conjugates for synergistic anticancer activity of camptothecin and doxorubicin combinations
Camacho, K. M.; Menegatti, S.; Mitragotri, S. Nanomedicine (Lond) 2016, 11 (9), 1139-1151.

Role of nanoparticle size, shape and surface chemistry in oral drug delivery
Banerjee, A.; Qi, J.; Gogoi, R.; Wong, J.; Mitragotri, S. J Control Release 2016, 238, 176-185.

Intestinal mucoadhesive devices for oral delivery of insulin
Banerjee, A.; Lee, J.; Mitragotri, S. Bioeng Transl Med 2016, 1 (3), 338-346.

Nanoparticles in the clinic
Anselmo, A. C.; Mitragotri, S. Bioeng Transl Med 2016, 1 (1), 10-29.

Nucleic acid delivery into skin for the treatment of skin disease: Proofs-of-concept, potential impact, and remaining challenges
Zakrewsky, M.; Kumar, S.; Mitragotri, S. J Control Release 2015, 219, 445-456.

Ultrasonic delivery of silica-gold nanoshells for photothermolysis of sebaceous glands in humans: Nanotechnology from the bench to clinic
Paithankar, D.; Hwang, B. H.; Munavalli, G.; Kauvar, A.; Lloyd, J.; Blomgren, R.; Faupel, L.; Meyer, T.; Mitragotri, S. J Control Release 2015, 206, 30-36.

Journal of Drug Targeting Life Time Achievement Award for Prof. Robert Langer
Mitragotri, S.; Hanes, J. J Drug Target 2015, 23 (7-8), 579.

Accelerating the Translation of Nanomaterials in Biomedicine
Mitragotri, S.; Anderson, D. G.; Chen, X.; Chow, E. K.; Ho, D.; Kabanov, A. V.; Karp, J. M.; Kataoka, K.; Mirkin, C. A.; Petrosko, S. H.; et al. ACS Nano 2015, 9 (7), 6644-6654.

Synthesis and characterization of a self-fluorescent hyaluronic acid-based gel for dermal applications
Menegatti, S.; Ruocco, N.; Kumar, S.; Zakrewsky, M.; Sanchez De Oliveira, J.; Helgeson, M. E.; Leal, G. L.; Mitragotri, S. Adv Healthc Mater 2015, 4 (15), 2297-2305.

Peptides as skin penetration enhancers: mechanisms of action
Kumar, S.; Zakrewsky, M.; Chen, M.; Menegatti, S.; Muraski, J. A.; Mitragotri, S. J Control Release 2015, 199, 168-178.

Enhanced epidermal localization of topically applied steroids using SPACE peptide
Kumar, S.; Chen, M.; Anselmo, A. C.; Muraski, J. A.; Mitragotri, S. Drug Deliv Transl Res 2015, 5 (5), 523-530.

Shape and size-dependent immune response to antigen-carrying nanoparticles
Kumar, S.; Anselmo, A. C.; Banerjee, A.; Zakrewsky, M.; Mitragotri, S. J Control Release 2015, 220 (Pt A), 141-148.

Topical delivery of Cyclosporine A into the skin using SPACE-peptide
Chen, M.; Kumar, S.; Anselmo, A. C.; Gupta, V.; Slee, D. H.; Muraski, J. A.; Mitragotri, S. J Control Release 2015, 199, 190-197.

Synergistic antitumor activity of camptothecin-doxorubicin combinations and their conjugates with hyaluronic acid
Camacho, K. M.; Kumar, S.; Menegatti, S.; Vogus, D. R.; Anselmo, A. C.; Mitragotri, S .J Control Release 2015, 210, 198-207.

Elasticity of nanoparticles influences their blood circulation, phagocytosis, endocytosis, and targeting
Anselmo, A. C.; Zhang, M.; Kumar, S.; Vogus, D. R.; Menegatti, S.; Helgeson, M. E.; Mitragotri, S. ACS Nano 2015, 9 (3), 3169-3177.

A Review of Clinical Translation of Inorganic Nanoparticles
Anselmo, A. C.; Mitragotri, S. AAPS J 2015, 17 (5), 1041-1054.

Exploiting shape, cellular-hitchhiking and antibodies to target nanoparticles to lung endothelium: Synergy between physical, chemical and biological approaches
Anselmo, A. C.; Kumar, S.; Gupta, V.; Pearce, A. M.; Ragusa, A.; Muzykantov, V.; Mitragotri, S. Biomaterials 2015, 68, 1-8.

Monocyte-mediated delivery of polymeric backpacks to inflamed tissues: a generalized strategy to deliver drugs to treat inflammation
Anselmo, A. C.; Gilbert, J. B.; Kumar, S.; Gupta, V.; Cohen, R. E.; Rubner, M. F.; Mitragotri, S. J Control Release 2015, 199, 29-36.

Ionic liquids as a class of materials for transdermal delivery and pathogen neutralization
Zakrewsky, M.; Lovejoy, K. S.; Kern, T. L.; Miller, T. E.; Le, V.; Nagy, A.; Goumas, A. M.; Iyer, R. S.; Del Sesto, R. E.; Koppisch, A. T.; et al.  Proc Natl Acad Sci U S A 2014, 111 (37), 13313-13318.

MoS(2) field-effect transistor for next-generation label-free biosensors
Sarkar, D.; Liu, W.; Xie, X.; Anselmo, A. C.; Mitragotri, S.; Banerjee, K. ACS Nano 2014, 8 (4), 3992-4003.

Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies
Mitragotri, S.; Burke, P. A.; Langer, R. Nat Rev Drug Discov 2014, 13 (9), 655-672.

Vascular targeting of nanocarriers: perplexing aspects of the seemingly straightforward paradigm
Howard, M.; Zern, B. J.; Anselmo, A. C.; Shuvaev, V. V.; Mitragotri, S.; Muzykantov, V. ACS Nano 2014, 8 (5), 4100-4132.

Topical delivery of siRNA into skin using SPACE-peptide carriers
Chen, M.; Zakrewsky, M.; Gupta, V.; Anselmo, A. C.; Slee, D. H.; Muraski, J. A.; Mitragotri, S. J Control Release 2014, 179, 33-41.

Topical delivery of hyaluronic acid into skin using SPACE-peptide carriers
Chen, M.; Gupta, V.; Anselmo, A. C.; Muraski, J. A.; Mitragotri, S. J Control Release 2014, 173, 67-74.

Challenges associated with Penetration of Nanoparticles across Cell and Tissue Barriers: A Review of Current Status and Future Prospects
Barua, S.; Mitragotri, S.  Nano Today 2014, 9 (2), 223-243.

Platelet-like nanoparticles: mimicking shape, flexibility, and surface biology of platelets to target vascular injuries
Anselmo, A. C.; Modery-Pawlowski, C. L.; Menegatti, S.; Kumar, S.; Vogus, D. R.; Tian, L. L.; Chen, M.; Squires, T. M.; Sen Gupta, A.; Mitragotri, S.  ACS Nano 2014, 8 (11), 11243-11253.

An overview of clinical and commercial impact of drug delivery systems
Anselmo, A. C.; Mitragotri, S. J Control Release 2014, 190, 15-28.

Cell-mediated delivery of nanoparticles: taking advantage of circulatory cells to target nanoparticles
Anselmo, A. C.; Mitragotri, S. J Control Release 2014, 190, 531-541.

Synthesis of protein-based, rod-shaped particles from spherical templates using layer-by-layer assembly
Zhou, Z.; Anselmo, A. C.; Mitragotri, S.  Adv Mater 2013, 25 (19), 2723-2727.

Diagnostic opportunities based on skin biomarkers
Paliwal, S.; Hwang, B. H.; Tsai, K. Y.; Mitragotri, S.  Eur J Pharm Sci 2013, 50 (5), 546-556.

Approaches to synthetic platelet analogs
Modery-Pawlowski, C. L.; Tian, L. L.; Pan, V.; McCrae, K. R.; Mitragotri, S.; Sen Gupta, A. Biomaterials 2013, 34 (2), 526-541.

Devices for overcoming biological barriers: the use of physical forces to disrupt the barriers
Mitragotri, S. Adv Drug Deliv Rev 2013, 65 (1), 100-103.

Engineering approaches to transdermal drug delivery: a tribute to contributions of prof. Robert Langer
Mitragotri, S. Skin Pharmacol Physiol 2013, 26 (4-6), 263-276.

Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium
Kolhar, P.; Anselmo, A. C.; Gupta, V.; Pant, K.; Prabhakarpandian, B.; Ruoslahti, E.; Mitragotri, S. Proc Natl Acad Sci U S A 2013, 110 (26), 10753-10758.

Optimized lysis buffer reagents for solubilization and preservation of proteins from cells and tissues
Hwang, B. H.; Tsai, K. Y.; Mitragotri, S. Drug Deliv Transl Res 2013, 3 (5), 428-436.

Mucoadhesive intestinal devices for oral delivery of salmon calcitonin
Gupta, V.; Hwang, B. H.; Lee, J.; Anselmo, A. C.; Doshi, N.; Mitragotri, S. J Control Release 2013, 172 (3), 753-762.

A permeation enhancer for increasing transport of therapeutic macromolecules across the intestine
Gupta, V.; Hwang, B. H.; Doshi, N.; Mitragotri, S. J Control Release 2013, 172 (2), 541-549.

Permeation of insulin, calcitonin and exenatide across Caco-2 monolayers: measurement using a rapid, 3-day system
Gupta, V.; Doshi, N.; Mitragotri, S. PLoS One 2013, 8 (2), e57136.

Particle shape enhances specificity of antibody-displaying nanoparticles
Barua, S.; Yoo, J. W.; Kolhar, P.; Wakankar, A.; Gokarn, Y. R.; Mitragotri, S. Proc Natl Acad Sci U S A 2013, 110 (9), 3270-3275.

Synergistic targeting of cell membrane, cytoplasm, and nucleus of cancer cells using rod-shaped nanoparticles
Barua, S.; Mitragotri, S.  ACS Nano 2013, 7 (11), 9558-9570.

Multifunctional nanoparticles for drug delivery and molecular imaging
Bao, G.; Mitragotri, S.; Tong, S. Annu Rev Biomed Eng 2013, 15, 253-282.

Delivering nanoparticles to lungs while avoiding liver and spleen through adsorption on red blood cells
Anselmo, A. C.; Gupta, V.; Zern, B. J.; Pan, D.; Zakrewsky, M.; Muzykantov, V.; Mitragotri, S. ACS Nano 2013, 7 (12), 11129-11137.

Glycosylation facilitates transdermal transport of macromolecules
Pino, C. J.; Gutterman, J. U.; Vonwil, D.; Mitragotri, S.; Shastri, V. P.  Proc Natl Acad Sci U S A 2012, 109 (52), 21283-21288.

Endocytic pathway rapidly delivers internalized molecules to lysosomes: an analysis of vesicle trafficking, clustering and mass transfer
Pangarkar, C.; Dinh, A. T.; Mitragotri, S. J Control Release 2012, 162 (1), 76-83.

Sampling of disease biomarkers from skin for theranostic applications
Ogura, M.; Paliwal, S.; Mitragotri, S.  Drug Deliv Transl Res 2012, 2 (2), 87-94.

Materials for drug delivery: innovative solutions to address complex biological hurdles
Mitragotri, S.; Lahann, J.  Adv Mater 2012, 24 (28), 3717-3723.

Spontaneous shape reconfigurations in multicompartmental microcylinders
Lee, K. J.; Yoon, J.; Rahmani, S.; Hwang, S.; Bhaskar, S.; Mitragotri, S.; Lahann, J.  Proc Natl Acad Sci U S A 2012, 109 (40), 16057-16062.

Mucociliary clearance of micro- and nanoparticles is independent of size, shape and charge--an ex vivo and in silico approach
Kirch, J.; Guenther, M.; Doshi, N.; Schaefer, U. F.; Schneider, M.; Mitragotri, S.; Lehr, C. M.  J Control Release 2012, 159 (1), 128-134.

Delivery systems for intradermal vaccination
Kim, Y. C.; Jarrahian, C.; Zehrung, D.; Mitragotri, S.; Prausnitz, M. R. Curr Top Microbiol Immunol 2012, 351, 77-112.

A reagent to facilitate protein recovery from cells and tissues
Hwang, B. H.; Doshi, N.; Tsai, K. Y.; Mitragotri, S.  Drug Deliv Transl Res 2012, 2 (5), 297-304.

Platelet mimetic particles for targeting thrombi in flowing blood
Doshi, N.; Orje, J. N.; Molins, B.; Smith, J. W.; Mitragotri, S.; Ruggeri, Z. M. Adv Mater 2012, 24 (28), 3864-3869.

Bio-inspired, bioengineered and biomimetic drug delivery carriers
Yoo, J. W.; Irvine, D. J.; Discher, D. E.; Mitragotri, S. Nat Rev Drug Discov 2011, 10 (7), 521-535.

Adaptive micro and nanoparticles: temporal control over carrier properties to facilitate drug delivery
Yoo, J. W.; Doshi, N.; Mitragotri, S. Adv Drug Deliv Rev 2011, 63 (14-15), 1247-1256.

Designing micro- and nano-particles for treating rheumatoid arthritis
Mitragotri, S.; Yoo, J. W. Arch Pharm Res 2011, 34 (11), 1887-1897.

Mathematical models of skin permeability: an overview
Mitragotri, S.; Anissimov, Y. G.; Bunge, A. L.; Frasch, H. F.; Guy, R. H.; Hadgraft, J.; Kasting, G. B.; Lane, M. E.; Roberts, M. S. Int J Pharm 2011, 418 (1), 115-129.

Delivery of polymeric particles into skin using needle-free liquid jet injectors
Michinaka, Y.; Mitragotri, S. J Control Release 2011, 153 (3), 249-254.

Polymer nanoneedle-mediated intracellular drug delivery
Kolhar, P.; Doshi, N.; Mitragotri, S. Small 2011, 7 (14), 2094-2100.

Effect of surfactant mixtures on skin structure and barrier properties
James-Smith, M. A.; Hellner, B.; Annunziato, N.; Mitragotri, S. Ann Biomed Eng 2011, 39 (4), 1215-1223.

Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer
Hsu, T.; Mitragotri, S. Proc Natl Acad Sci U S A 2011, 108 (38), 15816-15821.

Cell-based drug delivery devices using phagocytosis-resistant backpacks
Doshi, N.; Swiston, A. J.; Gilbert, J. B.; Alcaraz, M. L.; Cohen, R. E.; Rubner, M. F.; Mitragotri, S. Adv Mater 2011, 23 (12), H105-109.

Polymer particles that switch shape in response to a stimulus
Yoo, J. W.; Mitragotri, S. Proc Natl Acad Sci U S A 2010, 107 (25), 11205-11210.

Endocytosis and Intracellular Distribution of PLGA Particles in Endothelial Cells: Effect of Particle Geometry
Yoo, J. W.; Doshi, N.; Mitragotri, S. Macromol Rapid Commun 2010, 31 (2), 142-148.

Factors that control the circulation time of nanoparticles in blood: challenges, solutions and future prospects
Yoo, J. W.; Chambers, E.; Mitragotri, S. Curr Pharm Des 2010, 16 (21), 2298-2307.

Polymer particle shape independently influences binding and internalization by macrophages
Sharma, G.; Valenta, D. T.; Altman, Y.; Harvey, S.; Xie, H.; Mitragotri, S.; Smith, J. W. J Control Release 2010, 147 (3), 408-412.

Rapid sampling of molecules via skin for diagnostic and forensic applications
Paliwal, S.; Ogura, M.; Mitragotri, S. Pharm Res 2010, 27 (7), 1255-1263.

One-step acquisition of functional biomolecules from tissues
Paliwal, S.; Ogura, M.; Mitragotri, S. Proc Natl Acad Sci U S A 2010, 107 (33), 14627-14632.

Ultrasound-enhanced drug transport and distribution in the brain
Liu, Y.; Paliwal, S.; Bankiewicz, K. S.; Bringas, J. R.; Heart, G.; Mitragotri, S.; Prausnitz, M. R. AAPS PharmSciTech 2010, 11 (3), 1005-1017.

Transcutaneous immunization: an overview of advantages, disease targets, vaccines, and delivery technologies
Karande, P.; Mitragotri, S. Annu Rev Chem Biomol Eng 2010, 1, 175-201.

Flow and adhesion of drug carriers in blood vessels depend on their shape: a study using model synthetic microvascular networks
Doshi, N.; Prabhakarpandian, B.; Rea-Ramsey, A.; Pant, K.; Sundaram, S.; Mitragotri, S. J Control Release 2010, 146 (2), 196-200.

Macrophages recognize size and shape of their targets
Doshi, N.; Mitragotri, S. PLoS One 2010, 5 (4), e10051.

Needle-shaped polymeric particles induce transient disruption of cell membranes
Doshi, N.; Mitragotri, S. J R Soc Interface 2010, 7 Suppl 4, S403-410.

Novel topical microbicides through combinatorial strategies
Arora, A.; Mitragotri, S. Pharm Res 2010, 27 (7), 1264-1272.

Multicomponent chemical enhancer formulations for transdermal drug delivery: more is not always better
Arora, A.; Kisak, E.; Karande, P.; Newsam, J.; Mitragotri, S. J Control Release 2010, 144 (2), 175-180

Dynamic control of needle-free jet injection
Stachowiak, J. C.; Li, T. H.; Arora, A.; Mitragotri, S.; Fletcher, D. A. J Control Release 2009, 135 (2), 104-112.

Physical approaches to biomaterial design
Mitragotri, S.; Lahann, J. Nat Mater 2009, 8 (1), 15-23.

In drug delivery, shape does matter
Mitragotri, S. Pharm Res 2009, 26 (1), 232-234.

Enhancement of transdermal drug delivery via synergistic action of chemicals
Karande, P.; Mitragotri, S. Biochim Biophys Acta 2009, 1788 (11), 2362-2373.

Transcutaneous immunization using common chemicals
Karande, P.; Arora, A.; Pham, T. K.; Stevens, D.; Wojicki, A.; Mitragotri, S. J Control Release 2009, 138 (2), 134-140.

Red blood cell-mimicking synthetic biomaterial particles
Doshi, N.; Zahr, A. S.; Bhaskar, S.; Lahann, J.; Mitragotri, S. Proc Natl Acad Sci U S A 2009, 106 (51), 21495-21499.

Shape induced inhibition of phagocytosis of polymer particles
Champion, J. A.; Mitragotri, S. Pharm Res 2009, 26 (1), 244-249.

Mechanistic analysis of chemical permeation enhancers for oral drug delivery
Whitehead, K.; Mitragotri, S. Pharm Res 2008, 25 (6), 1412-1419.

Safe and effective permeation enhancers for oral drug delivery
Whitehead, K.; Karr, N.; Mitragotri, S. Pharm Res 2008, 25 (8), 1782-1788.

Discovery of synergistic permeation enhancers for oral drug delivery
Whitehead, K.; Karr, N.; Mitragotri, S. J Control Release 2008, 128 (2), 128-133.

Therapeutic opportunities in biological responses of ultrasound
Paliwal, S.; Mitragotri, S. Ultrasonics 2008, 48 (4), 271-278.

Low-frequency sonophoresis: current status and future prospects
Ogura, M.; Paliwal, S.; Mitragotri, S. Adv Drug Deliv Rev 2008, 60 (10), 1218-1223.

Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers Muro, S.; Garnacho, C.; Champion, J. A.; Leferovich, J.; Gajewski, C.; Schuchman, E. H.; Mitragotri, S.; Muzykantov, V. R. Mol Ther 2008, 16 (8), 1450-1458.

Role of particle size in phagocytosis of polymeric microspheres
Champion, J. A.; Walker, A.; Mitragotri, S. Pharm Res 2008, 25 (8), 1815-1821.

Micro-scale devices for transdermal drug delivery
Arora, A.; Prausnitz, M. R.; Mitragotri, S. Int J Pharm 2008, 364 (2), 227-236.

Temperature dependence of skin permeability to hydrophilic and hydrophobic solutes
Mitragotri, S. J Pharm Sci 2007, 96 (7), 1832-1839.

Synergistic effects of chemical enhancers on skin permeability: a case study of sodium lauroylsarcosinate and sorbitan monolaurate
Karande, P.; Jain, A.; Arora, A.; Ho, M. J.; Mitragotri, S. Eur J Pharm Sci 2007, 31 (1), 1-7.

Identification of peptide ligands facilitating nanoparticle attachment to erythrocytes
Hall, S. S.; Mitragotri, S.; Daugherty, P. S. Biotechnol Prog 2007, 23 (3), 749-754.

Modeling of pattern regulation in melanophores
Dinh, A. T.; Theofanous, T.; Mitragotri, S. J Theor Biol 2007, 244 (1), 141-153.

Understanding intracellular transport processes pertinent to synthetic gene delivery via stochastic simulations and sensitivity analyses
Dinh, A. T.; Pangarkar, C.; Theofanous, T.; Mitragotri, S. Biophys J 2007, 92 (3), 831-846.

Particle shape: a new design parameter for micro- and nanoscale drug delivery carriers
Champion, J. A.; Katare, Y. K.; Mitragotri, S. J Control Release 2007, 121 (1-2), 3-9.

Making polymeric micro- and nanoparticles of complex shapes
Champion, J. A.; Katare, Y. K.; Mitragotri, S. Proc Natl Acad Sci U S A 2007, 104 (29), 11901-11904.

Long circulating nanoparticles via adhesion on red blood cells: mechanism and extended circulation.
Chambers, E.; Mitragotri, S. Exp Biol Med (Maywood) 2007, 232 (7), 958-966.

Needle-free delivery of macromolecules across the skin by nanoliter-volume pulsed microjets
Arora, A.; Hakim, I.; Baxter, J.; Rathnasingham, R.; Srinivasan, R.; Fletcher, D. A.; Mitragotri, S. Proc Natl Acad Sci U S A 2007, 104 (11), 4255-4260.

Ultrasound-induced cavitation: applications in drug and gene delivery
Paliwal, S.; Mitragotri, S. Expert Opin Drug Deliv 2006, 3 (6), 713-726.

Low-frequency sonophoresis: ultrastructural basis for stratum corneum permeability assessed using quantum dots
Paliwal, S.; Menon, G. K.; Mitragotri, S. J Invest Dermatol 2006, 126 (5), 1095-1101.

Current status and future prospects of needle-free liquid jet injectors
Mitragotri, S. Nat Rev Drug Discov 2006, 5 (7), 543-548.

Evaluation of chemical enhancers in the transdermal delivery of lidocaine
Lee, P. J.; Ahmad, N.; Langer, R.; Mitragotri, S.; Prasad Shastri, V. Int J Pharm 2006, 308 (1-2), 33-39.

Relationships between skin's electrical impedance and permeability in the presence of chemical enhancers
Karande, P.; Jain, A.; Mitragotri, S. J Control Release 2006, 110 (2), 307-313.

Insights into synergistic interactions in binary mixtures of chemical permeation enhancers for transdermal drug delivery
Karande, P.; Jain, A.; Mitragotri, S. J Control Release 2006, 115 (1), 85-93.

Theory of spatial patterns of intracellular organelles
Dinh, A. T.; Pangarkar, C.; Theofanous, T.; Mitragotri, S. Biophys J 2006, 90 (10), L67-69.

Role of target geometry in phagocytosis
Champion, J. A.; Mitragotri, S. Proc Natl Acad Sci U S A 2006, 103 (13), 4930-4934.

Needle-free liquid jet injections: mechanisms and applications
Baxter, J.; Mitragotri, S. Expert Rev Med Devices 2006, 3 (5), 565-574.

Low-frequency ultrasound as a transcutaneous immunization adjuvant
Tezel, A.; Paliwal, S.; Shen, Z.; Mitragotri, S. Vaccine 2005, 23 (29), 3800-3807.

Dynamics and spatial organization of endosomes in mammalian cells
Pangarkar, C.; Dinh, A. T.; Mitragotri, S. Phys Rev Lett 2005, 95 (15), 158101.

Induction of cancer-specific cytotoxicity towards human prostate and skin cells using quercetin and ultrasound
Paliwal, S.; Sundaram, J.; Mitragotri, S. Br J Cancer 2005, 92 (3), 499-502.

Healing sound: the use of ultrasound in drug delivery and other therapeutic applications
Mitragotri, S. Nat Rev Drug Discov 2005, 4 (3), 255-260.

Immunization without needles
Mitragotri, S. Nat Rev Immunol 2005, 5 (12), 905-916.

Design principles of chemical penetration enhancers for transdermal drug delivery
Karande, P.; Jain, A.; Ergun, K.; Kispersky, V.; Mitragotri, S. Proc Natl Acad Sci U S A 2005, 102 (13), 4688-4693.

A model for intracellular trafficking of adenoviral vectors
Dinh, A. T.; Theofanous, T.; Mitragotri, S. Biophys J 2005, 89 (3), 1574-1588.

Jet-induced skin puncture and its impact on needle-free jet injections: experimental studies and a predictive model
Baxter, J.; Mitragotri, S. J Control Release 2005, 106 (3), 361-373.

Oral delivery of macromolecules using intestinal patches: applications for insulin delivery
Whitehead, K.; Shen, Z.; Mitragotri, S. J Control Release 2004, 98 (1), 37-45.

Topical delivery of anti-sense oligonucleotides using low-frequency sonophoresis
Tezel, A.; Dokka, S.; Kelly, S.; Hardee, G. E.; Mitragotri, S. Pharm Res 2004, 21 (12), 2219-2225.

Investigations of needle-free jet injections
Schramm-Baxter, J. R.; Mitragotri, S. Conf Proc IEEE Eng Med Biol Soc 2004, 2004, 3543-3546.

Needle-free jet injections: dependence of jet penetration and dispersion in the skin on jet power
Schramm-Baxter, J.; Mitragotri, S. J Control Release 2004, 97 (3), 527-535.

Jet injection into polyacrylamide gels: investigation of jet injection mechanics
Schramm-Baxter, J.; Katrencik, J.; Mitragotri, S. J Biomech 2004, 37 (8), 1181-1188.

Current status and future potential of transdermal drug delivery
Prausnitz, M. R.; Mitragotri, S.; Langer, R. Nat Rev Drug Discov 2004, 3 (2), 115-124.

Low-frequency sonophoresis: a review
Mitragotri, S.; Kost, J. Adv Drug Deliv Rev 2004, 56 (5), 589-601.

Breaking the skin barrier
Mitragotri, S. Adv Drug Deliv Rev 2004, 56 (5), 555-556.

Sonophoresis: a 50-year journey
Mitragotri, S. Drug Discov Today 2004, 9 (17), 735-736.

Discovery of transdermal penetration enhancers by high-throughput screening
Karande, P.; Jain, A.; Mitragotri, S. Nat Biotechnol 2004, 22 (2), 192-197.

Prolonged circulation of large polymeric nanoparticles by non-covalent adsorption on erythrocytes
Chambers, E.; Mitragotri, S. J Control Release 2004, 100 (1), 111-119.

Description of transdermal transport of hydrophilic solutes during low-frequency sonophoresis based on a modified porous pathway model
Tezel, A.; Sens, A.; Mitragotri, S. J Pharm Sci 2003, 92 (2), 381-393.

On the origin of size-dependent tortuosity for permeation of hydrophilic solutes across the stratum corneum
Tezel, A.; Mitragotri, S. J Control Release 2003, 86 (1), 183-186.

Interactions of inertial cavitation bubbles with stratum corneum lipid bilayers during low-frequency sonophoresis
Tezel, A.; Mitragotri, S. Biophys J 2003, 85 (6), 3502-3512.

An experimental and theoretical analysis of ultrasound-induced permeabilization of cell membranes
Sundaram, J.; Mellein, B. R.; Mitragotri, S. Biophys J 2003, 84 (5), 3087-3101.

Modeling skin permeability to hydrophilic and hydrophobic solutes based on four permeation pathways
Mitragotri, S. J Control Release 2003, 86 (1), 69-92.

A reversibly switching surface
Lahann, J.; Mitragotri, S.; Tran, T. N.; Kaido, H.; Sundaram, J.; Choi, I. S.; Hoffer, S.; Somorjai, G. A.; Langer, R. Science 2003, 299 (5605), 371-374.

Dependence of skin permeability on contact area
Karande, P.; Mitragotri, S. Pharm Res 2003, 20 (2), 257-263.

Synergistic effect of low-frequency ultrasound and surfactants on skin permeability
Tezel, A.; Sens, A.; Tuchscherer, J.; Mitragotri, S. J Pharm Sci 2002, 91 (1), 91-100.

Investigations of the role of cavitation in low-frequency sonophoresis using acoustic spectroscopy
Tezel, A.; Sens, A.; Mitragotri, S. J Pharm Sci 2002, 91 (2), 444-453.

Incorporation of lipophilic pathways into the porous pathway model for describing skin permeabilization during low-frequency sonophoresis
Tezel, A.; Sens, A.; Mitragotri, S. J Control Release 2002, 83 (1), 183-188.

A theoretical analysis of low-frequency sonophoresis: dependence of transdermal transport pathways on frequency and energy density
Tezel, A.; Sens, A.; Mitragotri, S. Pharm Res 2002, 19 (12), 1841-1846.

Porous resins as a cavitation enhancer for low-frequency sonophoresis
Terahara, T.; Mitragotri, S.; Langer, R. J Pharm Sci 2002, 91 (3), 753-759.

Dependence of low-frequency sonophoresis on ultrasound parameters; distance of the horn and intensity
Terahara, T.; Mitragotri, S.; Kost, J.; Langer, R. Int J Pharm 2002, 235 (1-2), 35-42.

Intestinal patches for oral drug delivery
Shen, Z.; Mitragotri, S. Pharm Res 2002, 19 (4), 391-395.

Transdermal drug delivery by jet injectors: energetics of jet formation and penetration
Schramm, J.; Mitragotri, S. Pharm Res 2002, 19 (11), 1673-1679.

A theoretical analysis of permeation of small hydrophobic solutes across the stratum corneum based on Scaled Particle Theory
Mitragotri, S. J Pharm Sci 2002, 91 (3), 744-752.

High throughput screening of transdermal formulations
Karande, P.; Mitragotri, S. Pharm Res 2002, 19 (5), 655-660.

Frequency dependence of sonophoresis
Tezel, A.; Sens, A.; Tuchscherer, J.; Mitragotri, S. Pharm Res 2001, 18 (12), 1694-1700.

Theoretical description of transdermal transport of hydrophilic permeants: application to low-frequency sonophoresis
Tang, H.; Mitragotri, S.; Blankschtein, D.; Langer, R. J Pharm Sci 2001, 90 (5), 545-568.

Transdermal delivery of heparin and low-molecular weight heparin using low-frequency ultrasound
Mitragotri, S.; Kost, J. Pharm Res 2001, 18 (8), 1151-1156.

Effect of therapeutic ultrasound on partition and diffusion coefficients in human stratum corneum
Mitragotri, S. J Control Release 2001, 71 (1), 23-29.

Effect of bilayer distruption on transdermal transport of low-molecular weight hydrophobic solutes
Mitragotri, S. Pharm Res 2001, 18 (7), 1018-1023.

Synergistic effect of low-frequency ultrasound and sodium lauryl sulfate on transdermal transport
Mitragotri, S.; Ray, D.; Farrell, J.; Tang, H.; Yu, B.; Kost, J.; Blankschtein, D.; Langer, R. J Pharm Sci 2000, 89 (7), 892-900.

Low-frequency sonophoresis: a noninvasive method of drug delivery and diagnostics
Mitragotri, S.; Kost, J. Biotechnol Prog 2000, 16 (3), 488-492.

Determination of threshold energy dose for ultrasound-induced transdermal drug transport
Mitragotri, S.; Farrell, J.; Tang, H.; Terahara, T.; Kost, J.; Langer, R. J Control Release 2000, 63 (1-2), 41-52.

Transdermal extraction of analytes using low-frequency ultrasound
Mitragotri, S.; Coleman, M.; Kost, J.; Langer, R. Pharm Res 2000, 17 (4), 466-470.

Analysis of ultrasonically extracted interstitial fluid as a predictor of blood glucose levels
Mitragotri, S.; Coleman, M.; Kost, J.; Langer, R. J Appl Physiol (1985) 2000, 89 (3), 961-966.

In situ determination of partition and diffusion coefficients in the lipid bilayers of stratum corneum
Mitragotri, S. Pharm Res 2000, 17 (8), 1026-1029.

Synergistic effect of enhancers for transdermal drug delivery
Mitragotri, S. Pharm Res 2000, 17 (11), 1354-1359.

Combined effect of low-frequency ultrasound and iontophoresis: applications for transdermal heparin delivery
Le, L.; Kost, J.; Mitragotri, S. Pharm Res 2000, 17 (9), 1151-1154.

Transdermal monitoring of glucose and other analytes using ultrasound
Kost, J.; Mitragotri, S.; Gabbay, R. A.; Pishko, M.; Langer, R. Nat Med 2000, 6 (3), 347-350.

An analysis of the size selectivity of solute partitioning, diffusion, and permeation across lipid bilayers.
Mitragotri, S.; Johnson, M. E.; Blankschtein, D.; Langer, R. Biophys J 1999, 77 (3), 1268-1283.

An explanation for the variation of the sonophoretic transdermal transport enhancement from drug to drug.
Mitragotri, S.; Blankschtein, D.; Langer, R. J Pharm Sci 1997, 86 (10), 1190-1192.

Transdermal drug delivery using low-frequency sonophoresis.
Mitragotri, S.; Blankschtein, D.; Langer, R. Pharm Res 1996, 13 (3), 411-420.

Synergistic effect of electric field and ultrasound on transdermal transport.
Kost, J.; Pliquett, U.; Mitragotri, S.; Yamamoto, A.; Langer, R.; Weaver, J. Pharm Res 1996, 13 (4), 633-638.

Synergistic effects of chemical enhancers and therapeutic ultrasound on transdermal drug delivery.
Johnson, M. E.; Mitragotri, S.; Patel, A.; Blankschtein, D.; Langer, R. J Pharm Sci 1996, 85 (7), 670-679.

A mechanistic study of ultrasonically-enhanced transdermal drug delivery.
Mitragotri, S.; Edwards, D. A.; Blankschtein, D.; Langer, R. J Pharm Sci 1995, 84 (6), 697-706.

Ultrasound-mediated transdermal protein delivery.
Mitragotri, S.; Blankschtein, D.; Langer, R. Science 1995, 269 (5225), 850-853.